Science or digital culture?

I have been following a conversation on Twitter following a New York Times opinion piece about humanism:

I might agree with Ted Underwood about the general point but is the anti-science part really anti-digital? Or rather than that a fear of the digital? If I remember correctly (and possibly I do not), Russian Formalism took a scientific approach to the structures in literature and Oulipo revelled in it.

This might say more about Western European and US humanism but I do wonder if this is a fear of the digital? Our society is becoming increasingly digital (which relies on an engineering / science base, yes) but culture is being placed into this framework or being born digital. Gradually humanism’s subjects are changing and becoming something else.